TGFBR2 polyclonal antibody (A01)
产品名称： TGFBR2 polyclonal antibody (A01)
英文名称： TGFBR2 polyclonal antibody (A01)
产品编号： H00007048-A01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a partial recombinant TGFBR2.
- Immunogen:
- TGFBR2 (NP_001020018, 62 a.a. ~ 165 a.a) partial recombinant protein with GST tag.
- Sequence:
- IVTDNNGAVKFPQLCKFCDVRFSTCDNQKSCMSNCSITSICEKPQEVCVAVWRKNDENITLETVCHDPKLPYHDFILEDAASPKCIMKEKKKPGETFFMCSCSS
- Host:
- Mouse
- Reactivity:
- Human, Mouse
- Storage Buffer:
- 50 % glycerol
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.55 KDa) .
- MSDS:
Download
- Publication Reference
- 1.
- Halofuginone enhances the radiation sensitivity of human tumor cell lines.
Cook JA, Choudhuri R, Degraff W, Gamson J, Mitchell JB.Cancer Lett. 2009 Aug 25. [Epub ahead of print]
- Applications
- Western Blot (Cell lysate)
- TGFBR2 polyclonal antibody (A01), Lot # 060525JCSI. Western Blot analysis of TGFBR2 expression in Raw 264.7.
- Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Entrez GeneID:
- 7048
- GeneBank Accession#:
- NM_001024847
- Protein Accession#:
- NP_001020018
- Gene Name:
- TGFBR2
- Gene Alias:
- AAT3,FAA3,LDS1B,LDS2B,MFS2,RIIC,TAAD2,TGFR-2,TGFbeta-RII
- Gene Description:
- transforming growth factor, beta receptor II (70/80kDa)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq
- Other Designations:
- TGF-beta receptor type IIB,TGF-beta type II receptor,transforming growth factor beta receptor type IIC,transforming growth factor, beta receptor II,transforming growth factor, beta receptor II (70-80kD)
- Related Disease
- Abnormalities, Multiple
- Aneurysm, Dissecting
- Aortic Aneurysm
- Aortic Aneurysm, Abdominal
- Aortic Aneurysm, Thoracic
- Aortic Rupture
- Asthma
- Atherosclerosis
- Autoimmune Diseases
- Breast cancer
- Breast Neoplasms
- Brief Psychiatric Rating Scale
- Carcinoma, Squamous Cell
- Cardiovascular Diseases
- Cleft Lip
- Cleft Palate
- Colon cancer
- Colonic Neoplasms
- Colorectal Neoplasms