[KO Validated] Peroxiredoxin 2 (PRDX2) Rabbit pAb (APR24462N)
产品名称: [KO Validated] Peroxiredoxin 2 (PRDX2) Rabbit pAb (APR24462N)
英文名称: [KO Validated] Peroxiredoxin 2 (PRDX2) Rabbit pAb (APR24462N)
产品编号: APR24462N
产品价格: null
产品产地: 美国
品牌商标: Leading Biology
更新时间: null
使用范围:
分子量:Calculated MW: 15kDa/21kDa Observed MW: 22KDa 细胞定位:Cytoplasm 稀释方法:WB 1:500 - 1:2000 IF 1:50 - 1:200 总结:This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13.