TPR monoclonal antibody (M01), clone 1A8
产品名称： TPR monoclonal antibody (M01), clone 1A8
英文名称： TPR monoclonal antibody (M01), clone 1A8
产品编号： H00007175-M01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant TPR.
- Immunogen:
- TPR (NP_003283, 1 a.a. ~ 98 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- MAAVLQQVLERTELNKLPKSVQNKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKE
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG1 Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.52 KDa) .
- MSDS:
Download
- Publication Reference
- 1.
- Herpes Simplex Virus Replication: Roles of Viral Proteins and Nucleoporins in Capsid-Nucleus Attachment.
Copeland AM, Newcomb WW, Brown JC.J Virol. 2009 Feb;83(4):1660-8. Epub 2008 Dec 10.
- 2.
- Quantitative Analysis of HIV-1 Infected CD4+ Cell Proteome: Dysregulated Cell Cycle Progression and Nuclear Transport Coincide with Robust Virus Production.
Chan EY, Qian WJ, Diamond DL, Liu T, Gritsenko MA, Monroe ME, Camp DG 2nd, Smith RD, Katze MG.J Virol. 2007 Jul;81(14):7571-83. Epub 2007 May 9.
- Applications
- Western Blot (Recombinant protein)
- Protocol Download
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Immunoperoxidase of monoclonal antibody to TPR on formalin-fixed paraffin-embedded human cerebellum. [antibody concentration 3 ug/ml]
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged TPR is approximately 0.1ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 7175
- GeneBank Accession#:
- NM_003292
- Protein Accession#:
- NP_003283
- Gene Name:
- TPR
- Gene Alias:
- -
- Gene Description:
- translocated promoter region (to activated MET oncogene)
- Omim ID:
- 189940
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein directly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias. [provided by RefSeq
- Other Designations:
- OTTHUMP00000033584,nuclear pore complex-associated protein TPR,nucleoprotein TPR,tumor potentiating region
- Gene Pathway