FITC标记的丝氨酸/苏氨酸SFRS9抗体
产品名称： FITC标记的丝氨酸/苏氨酸SFRS9抗体
英文名称： Anti-SFRS9/FITC
产品编号： HZ-17303R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-SFRS9/FITC Conjugated antibody
FITC标记的丝氨酸/苏氨酸SFRS9抗体
| 英文名称 | Anti-SFRS9/FITC |
| 中文名称 | FITC标记的丝氨酸/苏氨酸SFRS9抗体 |
| 别 名 | arginine/serine-rich 9; Pre mRNA splicing factor SRp30C; Pre-mRNA-splicing factor SRp30C; Serine/arginine-rich splicing factor 9; SFRS 9; Splicing factor; Splicing factor arginine/serine rich 9; splicing factor, arginine/serine-rich 9; splicing factor, arginine/serine-rich, 30-KD, C; SR splicing factor 9; SRP30C; SRSF9; SRSF9_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 激酶和磷酸酶 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Cow, Horse, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 26kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SFRS9 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two pseudogenes, one on chromosome 15 and the other on chromosome 21, have been found for this gene. [provided by RefSeq, Sep 2010] Function: Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses the splicing of MAPT/Tau exon 10. Subcellular Location: Nucleus. Cellular stresses such as heat shock may induce localization to discrete nuclear bodies termed SAM68 nuclear bodies (SNBs), HAP bodies, or stress bodies. Numerous splicing factors including SRSF1/SFRS1/SF2, SRSF7/SFRS7, SAFB and KHDRBS1/SAM68 accumulate at these structures, which may participate in the post-transcriptional regulation of mRNAs in stressed cells. Tissue Specificity: Expressed at high levels in the heart, kidney, pancreas and placenta, and at lower levels in the brain, liver, lung and skeletal muscle. Post-translational modifications: Extensively phosphorylated on serine residues in the RS domain. Similarity: Belongs to the splicing factor SR family. Contains 2 RRM (RNA recognition motif) domains. Database links: Entrez Gene: 8683 Human Entrez Gene: 108014 Mouse Entrez Gene: 100154637 Pig Entrez Gene: 288701 Rat Omim: 601943 Human SwissProt: Q13242 Human SwissProt: Q9D0B0 Mouse SwissProt: Q5PPI1 Rat Unigene: 706889 Human Unigene: 728777 Human Unigene: 287826 Mouse Unigene: 136718 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码的蛋白是富含丝氨酸/精氨酸(SR)的前mRNA剪接因子家族的成员，该家族构成了剪接体的一部分。这些因素中的每一个包含RNA结合基序（RRM）用于结合RNA和RS域结合其他蛋白质。RS域富含丝氨酸和精氨酸残基，有利于不同SR剪接因子之间的相互作用。除了对mRNA剪接起关键作用外，SR蛋白还被证明参与从细胞核的mRNA输出和翻译。两个假基因，一个在15号染色体上，另一个在21号染色体上，已经发现该基因。[ RefSeq，SEP 2010提供]