TXNRD1 (Human) Recombinant Protein
产品名称： TXNRD1 (Human) Recombinant Protein
英文名称： TXNRD1 (Human) Recombinant Protein
产品编号： P3509
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human TXNRD1 (NP_001087240, 161 a.a. - 647 a.a.) partial recombinant protein with His tag expressed in Escherichia coli.
- Sequence:
- MGSSHHHHHHSSGLVPRGSHMYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASILQAGC
- Theoretical MW (kDa):
- 55.7
- Form:
- Liquid
- Preparation Method:
- Escherichia coli expression system
- Purification:
- Conventional Chromatography
- Concentration:
- 0.5 mg/mL
- Purity:
- > 95% by SDS-PAGE
- Activity:
- Specific activity is 0.48-0.6 units/mL, and was measured in a coupled assay with DTNB and NADPH. The amount of TNB generated by NADPH was measured in absorbance at 412 nm.
- Storage Buffer:
- In PBS, pH 7.4 (10% glycerol)
- Storage Instruction:
- Store at 4°C for 1-2 weeks. For long term storage store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Loading 3 ug protein in 15% SDS-PAGE
- Application Image
- Functional Study
- SDS-PAGE
- Entrez GeneID:
- 7296
- Protein Accession#:
- NP_001087240
- Gene Name:
- TXNRD1
- Gene Alias:
- GRIM-12,MGC9145,TR,TR1,TRXR1,TXNR
- Gene Description:
- thioredoxin reductase 1
- Omim ID:
- 601112
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms. [provided by RefSeq
- Other Designations:
- KM-102-derived reductase-like factor,oxidoreductase,thioredoxin reductase GRIM-12
- Gene Pathway
- Related Disease