CXCR2 monoclonal antibody, clone 19-抗体-抗体-生物在线
亚诺法生技股份有限公司（Abnova)
CXCR2 monoclonal antibody, clone 19

CXCR2 monoclonal antibody, clone 19

商家询价

产品名称： CXCR2 monoclonal antibody, clone 19

英文名称： CXCR2 monoclonal antibody, clone 19

产品编号： MAB1850

产品价格： null

产品产地： 台湾

品牌商标： Abnova

更新时间： null

使用范围：

亚诺法生技股份有限公司（Abnova)
  • 联系人 :
  • 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
  • 邮编 : 11493
  • 所在区域 : 台湾
  • 电话 : +886-920**1152 点击查看
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  • 邮箱 : sales@abnova.com.tw
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic peptide of CXCR2.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 1-19 of human CXCR2.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Storage Buffer:
  • In PBS, pH 7.2
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Publication Reference
  • Applications
  • Western Blot
  • Immunohistochemistry
  • Immunocytochemistry
  • ELISA
  • Inhibition Assay
  • Flow Cytometry
  • Flow Cytometry
  • Isolated human neutrophils were incubated with 1.0 ug CXCR2 monoclonal antibody, clone 19 (Cat # MAB1850) followed by staining with goat F (ab') 2 anti-mouse IgG FITC [ shaded peak ] . Specificity of signal was confirmed by staining the neutrophils with 1.0 ug mouse IgG1 isotype control followed by the secondary antibody [ unshaded peak ] . The data indicate that approximately 98% of the isolated neutrophil population stains positive for this CXCR2 (M2 region).
  • Application Image
  • Western Blot
  • Immunohistochemistry
  • Immunocytochemistry
  • ELISA
  • Inhibition Assay
  • Gene Information
  • Entrez GeneID:
  • 3579
  • Gene Name:
  • CXCR2
  • Gene Alias:
  • CD182,CDw128b,CMKAR2,IL8R2,IL8RA,IL8RB
  • Gene Description:
  • chemokine (C-X-C motif) receptor 2
  • Gene Summary:
  • The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq
  • Other Designations:
  • C-X-C chemokine receptor type 2,CXC-R2,CXCR-2,CXCR2 gene for IL8 receptor type B,GRO/MGSA receptor,IL-8 receptor type 2,IL-8R B,chemokine (CXC) receptor 2,high affinity interleukin-8 receptor B,interleukin 8 receptor B,interleukin 8 receptor type 2,interl

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