Anti-SYT6/FITC Conjugated抗体-抗体-抗体-生物在线
上海钰博生物科技有限公司
Anti-SYT6/FITC Conjugated抗体

Anti-SYT6/FITC Conjugated抗体

商家询价

产品名称: Anti-SYT6/FITC Conjugated抗体

英文名称: Anti-SYT6/FITC

产品编号: YB--4175R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

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 Anti-SYT6/FITC Conjugated抗体

产品编号 YB-4175R-FITC
英文名称 Anti-SYT6/FITC
中文名称 FITC标记的突触蛋白6抗体
别    名 Synaptotagmin 6; Synaptotagmin VI; Synaptotagmin-6; Synaptotagmin6; SynaptotagminVI; Syt 6; Syt VI; Syt6; SYT6_HUMAN; SytVI.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 免疫学  神经生物学  信号转导  转运蛋白  细胞类型标志物  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 57kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Synaptotagmin VI (385-430aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The protein encoded by this gene belongs to the synaptotagmin family. Synaptotagmins share a common domain structure that includes a transmembrane domain and a cytoplasmic region composed of 2 C2 domains, and are involved in calcium-dependent exocytosis of synaptic vesicles. This protein has been shown to be a key component of the secretory machinery involved in acrosomal exocytosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2011]

Function:
May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. May mediate Ca(2+)-regulation of exocytosis in acrosomal reaction in sperm (By similarity). 

Subunit:
Homodimer (isoform 1). Isoform 1 forms heterodimers with SytIII, SytV and SytX. Interacts with STX1A, STX1B and STX2; the interaction is Ca(2+)-dependent. Isoform 2 is not able to form homodimer and heterodimers.

Subcellular Location:
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein. Isoform 1: Membrane; Single-pass membrane protein. Note=Localized predominantly to endoplasmic reticulum (ER) and/or Golgi-like perinuclear compartment. Isoform 2: Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein.

Similarity:
Belongs to the synaptotagmin family.
Contains 2 C2 domains.

Database links:

Entrez Gene: 148281 Human

Entrez Gene: 54524 Mouse

Entrez Gene: 60565 Rat

Omim: 607718 Human

SwissProt: Q5T7P8 Human

SwissProt: Q9R0N8 Mouse

SwissProt: Q62746 Rat

Unigene: 370963 Human

Unigene: 88818 Mouse

Unigene: 48074 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications