CASP1 polyclonal antibody-抗体-抗体-生物在线
亚诺法生技股份有限公司（Abnova)
CASP1 polyclonal antibody

CASP1 polyclonal antibody

商家询价

产品名称： CASP1 polyclonal antibody

英文名称： CASP1 polyclonal antibody

产品编号： PAB0811

产品价格： null

产品产地： 台湾

品牌商标： Abnova

更新时间： null

使用范围：

亚诺法生技股份有限公司（Abnova)
  • 联系人 :
  • 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
  • 邮编 : 11493
  • 所在区域 : 台湾
  • 电话 : +886-920**1152 点击查看
  • 传真 : 点击查看
  • 邮箱 : sales@abnova.com.tw
进入展台

  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against a synthetic peptide of CASP1.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human CASP1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • This antibody reacts with human caspase-1 precursor (also designated ICE), non cross-reactive with caspase-1 p10 or caspase-1 p20.
  • Form:
  • Liquid
  • Storage Buffer:
  • In PBS (0.2% gelatin, 0.1% sodium azide)
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Western Blot
  • Human caspase-1 precursor (also designated ICE) , non cross-reactive with caspase-1 p10 or caspase-1 p20.
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 834
  • Gene Name:
  • CASP1
  • Gene Alias:
  • ICE,IL1BC,P45
  • Gene Description:
  • caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
  • Gene Summary:
  • This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing of this gene results in five transcript variants encoding distinct isoforms. [provided by RefSeq
  • Other Designations:
  • CASP1 nirs variant 1,IL1B-convertase,caspase 1,caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase),interleukin 1-B converting enzyme,interleukin 1-beta convertase

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