DFFA MaxPab mouse polyclonal antibody (B01)
产品名称： DFFA MaxPab mouse polyclonal antibody (B01)
英文名称： DFFA MaxPab mouse polyclonal antibody (B01)
产品编号： H00001676-B01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human DFFA protein.
- Immunogen:
- DFFA (NP_004392, 1 a.a. ~ 331 a.a) full-length human protein.
- Sequence:
- MEVTGDAGVPESGEIRTLKPCLLRRNYSREQHGVAASCLEDLRSKACDILAIDKSLTPVTLVLAEDGTIVDDDDYFLCLPSNTKFVALASNEKWAYNNSDGGTAWISQESFDVDETDSGAGLKWKNVARQLKEDLSSIILLSEEDLQMLVDAPCSDLAQELRQSCATVQRLQHTLQQVLDQREEVRQSKQLLQLYLQALEKEGSLLSKQEESKAAFGEEVDAVDTGISRETSSDVALASHILTALREKQAPELSLSSQDLELVTKEDPKALAVALNWDIKKTETVQEACERELALRLQQTQSLHSLRSISASKASPPGDLQNPKRARQDPT
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- No additive
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- Note:
- For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
- MSDS:
Download
- Applications
- Western Blot (Tissue lysate)
- DFFA MaxPab polyclonal antibody. Western Blot analysis of DFFA expression in human liver.
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of DFFA expression in transfected 293T cell line (H00001676-T01) by DFFA MaxPab polyclonal antibody.
Lane 1: DFFA transfected lysate(36.41 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Immunofluorescence
enlarge this image- Immunofluorescence of purified MaxPab antibody to DFFA on HeLa cell. [antibody concentration 10 ug/ml]
- Protocol Download
- Entrez GeneID:
- 1676
- GeneBank Accession#:
- NM_004401
- Protein Accession#:
- NP_004392
- Gene Name:
- DFFA
- Gene Alias:
- DFF-45,DFF1,ICAD
- Gene Description:
- DNA fragmentation factor, 45kDa, alpha polypeptide
- Omim ID:
- 601882
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- DFF45,DNA fragmentation factor, 45 kD, alpha polypeptide,DNA fragmentation factor, 45 kD, alpha subunit,OTTHUMP00000001903,OTTHUMP00000001904
- Interactome
- Gene Pathway
- Related Disease